FDA Approved Non-Prescription Weight Loss Aid Only FDA Approved, Over-the-Counter Weight Loss Aid With Orlistat Helps Prevent Fat Be Absorbed alli Weight Loss Aid Includes: alli® Read Me First Guide alli® 120 ct Bottle (40 day supply) alli® Companion Guide Book. Helps you lose more weight than dieting alone. alli® is the only FDA approved, over-the-counter weight loss aid. alli® contains orlistat, which helps about 25% of the fat you eat from being absorbed. For every 2 pounds your lose through diet and exercise, alli® can help you lose one more. alli® (orlistat 60mg capsules) is a weight loss aid for overweight adults, 18 years and older, when used along with a reduced-calorie and low-fat diet. Follow label directions. alli® Companion Guide Book offers tips, tools and help for setting weight loss goals.